The Activity of 1,3,4 Thiadiazole Derivatives on the Soluble Oils

That Thiadiazoles derivative is biologically active as antimicrobial agents in cooling fluids.
 Derivatives of 1, 3, 4- thiadiazole have prepared:
 
 2-amino-3-[(2-amino-1, 4-thiadiazol-5-yl) dithio] propanoic acid.
 2-(2-Carbethoxyamino-1, 4-thiadiazol-5-yl)-thio acetic [(5-amino-1,3,4-thiadiazol-2-yl) acid
 The synthesized compounds been used against the microorganisms which found fluid industrial
 purposes by using media culture results showed that 1 and 3 are relatively highly killing bacteria from compound 2.
 pH samples had measured after addition salt well inhibitors (1,2,3) measurement revealed 1,2 exhibit high activity to inhibit growth bacteria.
 turbidity for such has also indicated given low or grow fluid.